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Here we show that CT recruits
2022-02-17

Here, we show that CT229 recruits multiple Rab GTPases and Rab effector proteins to the inclusion; the CT229 Inc protein redirects and intercepts host clathrin-coated vesicles (CCVs). CT229 is required for recruitment of transferrin (Tfn) positive CCV’s from the recycling pathway to the periphery of
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One of the mechanism of regulation of NO content in
2022-02-17

One of the mechanism of regulation of NO content in plant cells is it scavenging by GSH leading to formation of GSNO [59]. This reaction, depending on NO level and availability of glutatione in its reduced form, influences cellular redox potential by lowering GSH content and in consequence may impac
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Others demonstrated that Paneth cells maintain stem cell fun
2022-02-17

Others demonstrated that Paneth cells maintain stem cell function and crypt homeostasis by providing metabolic lactate to sustain the enhanced mitochondrial oxidative phosphorylation in the Lgr5+ ISCs (Rodriguez-Colman et al., 2017), which substantially agrees with our findings in this study. Furthe
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Using expression of TcMYH fused to
2022-02-17

Using expression of TcMYH fused to GFP, it was observed that MYH is present in the nucleus and in the mitochondrion of T. cruzi (Fig. 5). It is known that MYH protein from human, rat and mouse exhibits both mitochondrial and nuclear localization (Ichinoe et al., 2004, Lee et al., 2004, Nishioka et a
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Four polymorphic variants of Neil namely S C
2022-02-17

Four polymorphic variants of Neil1, namely, S82C (rs5745905), G83D (rs5745906), C136R (rs5745907) and D252N (rs5745926) were characterized by Roy et al. in 2007 (Table 1). Analyses of AP site incision on Tg containing oligonucleotide showed that S82C and D252N variants had wild type activity and car
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Studies dealing with the effects of ischemia
2022-02-17

Studies dealing with the effects of ischemia on EAATs have been previously reported, but some discrepancies in literature appear between them probably as a consequence of the different models, species, time of reperfusion after ischemia and age of the animals. Thus, in human, flecainide acetate str
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br Materials and methods br Results br
2022-02-17

Materials and methods Results Discussion l-glutamate is the major excitatory neurotransmitter in the brain, and is functionally involved in many processes of the nervous system which have been connected with several neurological diseases [4]. These conditions are characterized by the time-d
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br Materials and methods br Results br
2022-02-17

Materials and methods Results Discussion Quercetin is a relatively abundant bioactive flavonoid with a wide variety of documented physiological effects, which has gained popularity as a nutritional supplement [40]. There is increasing interest in quercetin's anticancer properties (for recen
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EHT 1864 australia As early as glucagon was shown to
2022-02-17

As early as 1957, glucagon was shown to increase EHT 1864 australia expenditure in rodents in both pair-feeding studies and through directly increasing oxygen consumption [23], [24]. This has more recently been confirmed in man, through indirect calorimetry during glucagon infusions [25], [26], [27
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br Competing interests br Acknowledgements
2022-02-17

Competing interests Acknowledgements Introduction - Factors Regulating Glucose Tolerance Strictly speaking, the incretin effect refers to the amplification of insulin secretion, which occurs when fluvastatin sodium synthesis is taken in orally as compared to infused intravenously [1]. Norm
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In sharp contrast to these genetically
2022-02-17

In sharp contrast to these genetically altered animals, there are two types of living fish that appear to lack Band 3 in their red blood cells. These are the Lamprey [45] and the Hagfish [46,47]. While these fish normally occupy their respective niches, the presumed compensatory mechanisms, as with
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br Methods br Results br Discussion
2022-02-17

Methods Results Discussion In this study, we investigated temperature effects on Vj-gating properties of two cardiac GJs. In the case of Cx45 GJs, increased temperature from 22 °C to 28 °C (or 32 °C) led to an accelerated Vj-dependent deactivation with little change in the extent of Vj-gati
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N-Acetylneuraminic acid Cellular inhibition is caused by
2022-02-17

Cellular inhibition is caused by the hyperpolarization of the cell and is mediated by both synaptic and extrasynaptic GABAARs. Synaptic GABAARs are sensitive to high concentrations of GABA released at the synapse and mediate phasic inhibition. In contrast, extrasynaptic GABAARs mediate tonic inhibit
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The deduced amino acid sequences of all scIPPSs
2022-02-16

The deduced amino Melanocyte stimulating hormone release inhibiting factor australia sequences of all scIPPSs display high similarity, and sequence alignments reveal seven conserved regions [2]. Regions II and VI contain the substrate-binding regions, with two characteristic aspartate-rich motifs (
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br Experimental br Acknowledgments br Human immunodeficiency
2022-02-16

Experimental Acknowledgments Human immunodeficiency virus-1 (HIV-1) is the causative agent of acquired immunodeficiency syndrome (AIDS), and without treatment results in a debilitating disease that cripples the immune system of the patient, increasing susceptibility to opportunistic diseases
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